Dan gives talk at
Université du Québec à Montréal
September 10, 2018
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Thanks so much to Claire Bénard for giving me the opportunity to present our work at
Welcome to the Shaye Lab
at the University of Illinois at Chicago
We study the cell biology and genetic regulation underlying biological tube formation
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Lab News and Blog
Dan gives talk at
New OrthoList compendium published
August 20, 2018
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OrthoList 2, our new comparative genomic analysis of human and worm genes has been published.
First Chicago Area Worm Meeting
May 24, 2018
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The first ChAWM, co-organized by Erik Anderson (Northwestern), Heng-Chi Lee and Paschalis Kratsios (U Chicago), and Dan (UIC) is happening today.
Federica Awarded a LASURI Fellowship
May 1, 2018
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Congratulation Federica! Please click on “Read More” for more information on the LASURI program.
Welcome Priyanka!
April 9, 2018
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Our newest lab member, Visiting Assistant Research Prof. Priyanka Shukla, joins us today.
For more information click on title or logo in each section below
The C.elegans excretory canal (ExCa) is a single-cell tube that provides an excellent model to study biological tube formation (tubulogenesis). Genes that regulate ExCa development have human homologs implicated in kidney and vascular disease. We use the ExCa to discover and study new tubulogenesis regulators.
Some genes that regulate ExCa tubulogenesis have been implicated in angiogenesis; the creation of new blood vessels from existing ones. We use human cell culture models to ask whether genes that we discover in C. elegans play roles in angiogenesis.
We are part of the Dept. of Physiology and Biophysics at the University of Illinois at Chicago (UIC). We are centrally located at the Illinois Medical District, and within walking distance of the University Village/Little Italy neighborhood.